Here I am describing only one technique of counting, examining, and sorting microscopic particles suspended in a stream of fluid. Its name is Flow cytometry
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Q1. What is Flow Focusing?
Ans. Flow Focusing is a technique to produce controlled size micro-spheres. In this technique the continues phase fluid exerts pressure & viscous stress; that force the dispersed phase fluid into a microthread. The breakup of the microthread then takes place inside of downstream of the orifice and we get micro size droplets.
Q2. What are the uses of Flow Focusing technique?
Ans.
(1) Microspheres have many applications in medicine, with the main uses being for the encapsulation of drugs. The target area could receive drug loaded microspheres either by passive means (trapping by size) or by active means (magnetic targeting) and slowly release the encapsulated drug over a desired time period, the extent of which is determined mainly by the drug's biological half-life. The drug distribution and final destiny of the microspheres is mainly depends on their size and surface charge.
(2)
A technique to produce controlled size micro-spheres
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About Student
- Rahul Yadav
- An Undergraduate student of Metallurgical engineering & materials science Dept, Indian Institute of Technology, Bombay, India
- ************************************************************************************************************ Our research group is using Flow Focusing technique to produce mono-sized micro-spheres which are capable of encapsulating clinically useful drugs. Such encapsulated microspheres would be very useful for the treatment of cancer patients. We are also interested in magnetic drug targeting, a situation in which a magnet outside the body is able to direct and concentrate drug-loaded magnetic particles inside distinct organs, tumours or tissues. Since magnetic particles of different sizes experience differently strong attraction to a magnet, only particles of identical size will provide for predictable targeting and full magnetic particle retention. ************************************************************************************************************
Discussion about Flow Focusing
Flow Focusing: Q&A
Q1. What is Flow Focusing?
Ans. Flow Focusing is a technique to produce controlled size micro-spheres. In this technique the continues phase fluid exerts pressure & viscous stress; that force the dispersed phase fluid into a microthread. The breakup of the microthread then takes place inside of downstream of the orifice and we get micro size droplets.
Q2. What are the uses of Flow Focusing technique?
Ans.
(1) Microspheres have many applications in medicine, with the main uses being for the encapsulation of drugs. The target area could receive drug loaded microspheres either by passive means (trapping by size) or by active means (magnetic targeting) and slowly release the encapsulated drug over a desired time period, the extent of which is determined mainly by the drug's biological half-life. The drug distribution and final destiny of the microspheres is mainly depends on their size and surface charge.
(2)
Material Science